Which is better: Isotonic or tablet OPC-3?

Millions of people enjoy the benefits of drinking a proprietary isotonic antioxidant called Isotonix OPC-3®. A tablet form of OPC-3® is not commercially available. However, for the purpose of testing, European researchers created a tablet version of OPC-3® to compare its assimilation (consumed with the equivalent amount of water) to the isotonic version. Phytotherapy Research e-published the compelling study results.

Both formulations of OPC-3® delivered antioxidant benefits by markedly reducing oxygen free radicals in blood plasma. However, the drinkable isotonic version of Isotonix OPC-3® measured 6 times higher than the tablet version within 10 minutes of consumption. After 20 minutes the isotonic formulation was approximately 4 times more bioavailable than the tablet. In fact, throughout the 4 hour investigation the isotonic formulation displayed a consistently superior level of performance.

As the chart indicates there was a much higher nutrient absorption and delivery in the drinkable isotonic formulation known as Isotonix OPC-3®.

Another clinical study found Isotonix OPC-3® dramatically reduced major cardiovascular risk factors in 61 individuals with metabolic syndrome over two months. Improvement occurred in blood pressure, total cholesterol, and fasting blood glucose. Supplementation with Isotonix OPC-3® resulted in a 52.1% drop in C-reactive proteins. C-reactive proteins are inflammation markers which predict cardiovascular risk. Comparatively, testing has shown that statin drugs produce 13-14% reductions in C-reactive proteins and often carry troubling side effects.

Naturally Improve Blood Pressure & Congestive Heart Failure

Results published from a 2010 clinical study in Italy found that using Pycnogenol®, along with CoenzymeQ10, significantly improved blood pressure and cardiovascular performance in participating subjects.

Pycnogenol® is a patented form of French maritime pine bark extract and has been part of hundreds of clinical studies due to its enormous range of health benefits. CoenzymeQ10 (CoQ10) is is a critically important vitamin-like substance, produced within the human body, that is essential for cellular activity.

The 53 subjects had stable congestive heart failure, mild to moderately high blood pressure and 75% were using three or more medications to manage their heart failure. The subjects given 12 weeks of Pycnogenol® and CoQ10 supplementation obtained the following results:

  • Significantly lower systolic and diastolic blood pressure
  • More than three-fold increase in treadmill walking distances
  • Substantial reduction in distal edema (edema of the extremities)
  • Improved heart rates and respiratory rates

In conclusion, researchers found: “The association of Pycnogenol and CoQ10 may offer an important therapeutic option with a very good tolerability that improves heart failure management without side effects.”

Isotonix OPC-3® is a synergistic blend of potent plant-based antioxidants and contains the only isotonic-capable Pycnogenol® on the market. This drinkable isotonic formula delivers up to 95% nutrient absorption within minutes of ingestion.  A separate clinical study conducted on subjects supplemented with Isotonix OPC-3® had significant cardiovascular performance improvements after 8 weeks.

Isotonix® CoQ10 offers similar bioavailability advantages and can even be mixed together with the OPC-3® and drank at the same time.

It’s here! A drinkable isotonic for Joints!

Approximately 46 million people in the United States (or 1 in every 4 to 5) suffer with some type of painful joint disease or condition. These conditions include arthritis, gout, lupus, fibromyalgia, bursitis, and stenosis.

Management of joint pain and stiffness can be costly and frustrating. Pain killers offer some relief, but do not stimulate healing. Pain medicines can also create gastrointestinal distress and potentially dangerous side effects when used long term. Clinical studies have observed joint benefits in several natural compounds that may actually improve joint mobility and comfort.

However, not all joint supplements are created equal.

Chondroitin and MSM (methylsulfonylmethane) are commonly used for joint issues, but are not consistently recommended. Chondroitin has some known negative side effects and men concerned with prostate cancer should carefully investigate before using. MSM is considered safe, however therapeutic doses are high (between 2-10 grams daily) making it impractical for many to use on a regular basis.

Three well established and clinically studied natural compounds for improving and maintaining joint function are Pycnogenol®, Hyaluronic Acid and Glucosamine.

Pycnogenol®:

A double-blind, randomized, placebo-controlled study observed that Pycnogenol® used daily for 3 months:

  • Reduced osteoarthritis symptoms by 56%
  • Reduced joint pain by 55%
  • Lowered need for pain medication by 58%
  • Gastrointestinal complications declined by 63%
  • Decreased edema in 79% of participants

Hyaluronic Acid:

Hyaluronic Acid is important in tissue lubrication, is a powerful antioxidant and improves cellular performance. Studies note Hyaluronic Acid for its ability to inhibit antithrombin which is involved in joint tissue destruction in rheumatoid arthritis. Anti-aging benefits of Hyaluronic Acid can also improve skin and hair as well.

Glucosamine:

Clinical studies found glucosamine worked better than ibuprofen for pain management. Glucosamine also has been observed to improve joint function and delay the progression of osteoarthritis. These effects were seen in as little as 2 weeks. Two independent studies found 1500 mgs. of daily oral Glucosamine prevented joint space narrowing in mild to moderate knee osteoarthritis.

Prime Joint Formula by Isotonix® is a drinkable joint health supplement that contains Pycnogenol®, Hyaluronic Acid and Glucosamine in an isotonic form.

Isotonix® products are drinkable isotonic solutions which absorb in a matter of minutes when taken as directed. These products are incredibly effective because they deliver up to 95% bioavailable nutrition. This type of delivery is much more effective than pills which can only provide 20-40% of their nutrients to the blood stream of healthy consumers. Isotonix® is also the only provider of Pycnogenol® as a drinkable isotonic.

Wonderful – Terrible – Prednisone

Prednisone is a synthetic form of corticosteroid that can be administered in topical, injectable, or oral form. Corticosteroids are a class of steroid’s which act like hormones that are produced by the adrenal gland.

Prednisone is prescribed to very effectively suppress immune system response when treating a variety of inflammatory diseases and disorders. This includes arthritis, eczema, some cancers, irritable bowel symptoms, asthma, allergic reactions, multiple sclerosis, Alzheimer’s, chronic pain conditions and many others.

When our bodies are under stress, a natural steroid hormone called cortisol is a released. Cortisol is part of the “fight or flight” response which causes changes to blood pressure, blood sugar, immune and inflammatory response. These changes are not harmful when the body has a chance to recover from the stress inducing event. Stress responses can become very problematic if triggered too frequently.

The immune system cannot operate properly under the influence of excessive cortisol. Impaired immunity leaves the door open to illness and disease. Because prednisone is a synthetic corticosteroid it should be used cautiously, infrequently, and sparingly to reduce the likelihood of complications. When used judiciously, it can be a wonderful drug.

However, when prednisone is taken for more than a few weeks, it causes the adrenal gland to shrink, producing fewer natural steroid hormones. That is why discontinuing prednisone and other corticosteroids much be done slowly so that the adrenal gland can return to normal production. Sudden drug withdrawal can trigger dangerous side effects. There are also some terrible possible side effects and complications which can occur when using prednisone:

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Combat Migraines with Isotonic Antioxidants

Woman SoldierMigraines plague approximately 30 million people in the United States with 75% of that number consisting of women.

The treatment of migraines has spurred the creation of a myriad of pain management centers, medications, books, diets, procedures and approaches.  Addressing the physiological and/or environmental causes and then determining the appropriate solution can be daunting at best. Fortunately, many people have found relief from migraines by using nutritional antioxidants and anti-inflammatories.

Free radicals destroy and damage cells. Our bodies are equipped to handle free radicals to a certain degree, but factors such as illness, toxins, and stress can overwhelm the normal production of cellular antioxidants. This results in an imbalance that can set the stage for migraines. Supporting cellular function and immune response with potent and well-researched antioxidants can not only inhibit migraines, it also contributes to disease resistance and anti-aging.

Using isotonic formulas are a terrific way of ingesting anti-inflammatories and antioxidants. Isotonic solutions are the perfect balance of solids to liquids which allows them to pass rapidly from the stomach to the small intestine for maximum absorption.

Some highly effective anti-inflammatories and antioxidants that migraine sufferers are often lacking in are:

  • Magnesium and Calcium
  • B-Complex
  • Oligomeric Proanthocyanidins (OPC’s)
  • Vitamin D
  • Coenzyme Q10 (CoQ10)
  • L-Tryptophan
  • Omega 3 Fish Oils

Fortunately all of these recommendations are available through SHOP.COM and meet these high standards. Drinkable, delicious and up to 95% absorbed these Isotonix® products, along with the others, are amazingly effective.

Isotonix Magnesium
Isotonix® Calcium Plus

Isotonix® Activated B-Complex
Isotonix OPC-3®
Isotonix® Vitamin D with K2
Isotonix® Coenzyme Q10
Isotonix® L-Tryptophan
HeartHealth™ Essential Omega 3 Fish Oil with Vitamin E

Boost Fertility for Men and Women with Vitamin D and OPC’s

Pregnant CoupleIn the United States over 6.2 million women struggle with infertility and the numbers are climbing. Up to 60% of couples have difficulty conceiving due to poor sperm motility. Supporting overall nutrition with high-quality, bioavailable nutrients is a safe, simple, and inexpensive approach to improving this condition. Clearing up underlying nutritional weaknesses will not only benefit fertility, it will improve overall health and increase longevity.

Two powerful health and fertility supplements for both men and women are Vitamin D and Oligomeric Procyanthocyanidins or (OPC’s).

Vitamin D continues to to be in the health spotlight due to the staggering number of people who are deficient in this important nutrient. The alarming correlation between hundreds of different illnesses/disorders and low levels of vitamin D has persuaded many health care professionals to encourage supplementation.

A recent study conducted with 84 infertile women found significantly higher rates of pregnancies occurred when blood serum levels of vitamin D were increased. Fertility specialist, Dr. Anne Clark, found that one third of men tested with fertility problems had below normal levels of vitamin D.

Adequate supplementation can fall short even though approximately half of the US population consumes some type of multi-vitamin. Many people don’t know that the US RDA (recommended daily allowance) of vitamins and minerals was established as minimum amounts to prevent the onset of disease due to severe deficiency for average healthy adult males. RDA’s were not intended as sufficient nutritional amounts to establish health in the general populace or to combat disease. So using only a basic multi-vitamin may still leave many people nutritionally malnourished.

Oligomeric Procyanthocyanidins (OPC’s) are a potent combination of bio-flavonoid antioxidants that inhibit cellular free radical damage. Additionally, OPC’s provide anti-inflammatory activity, cardiovascular and joint health, plus maintenance of healthy cholesterol, vascular, and blood glucose levels. OPC’s have been found to improve fertility in both men and women.

Isotonix® produces drinkable and delicious isotonic forms of both of these fertility enhancing supplements.  Isotonix® Vitamin D with K2 provides 5000 iu’s per dose of active and bioavailable vitamin D3 enhanced with vitamin K2.

Isotonix OPC-3® contains the only isotonic form of Pycnogenol® in the world. Pycnogenol® is a patented form of French maritime pine bark. A 2002 published study found sperm mobility was increased by 38% after just 90 days of supplementation with Pycnogenol®.

An isotonic formula dramatically increases nutrient delivery into the small intestine, which in turn improves the rate of absorption by as much as 95%! Drinking these nutrients in an isotonic form requires far less digestive effort and delivers more value than typical liquid, capsule, or tablet forms.

Rapid absorption, easy digestion, and great taste are just a few reasons why Isotonix® supplements, including the Isotonix® Prenatal Multivitamin and the line of Isotonix® Might-A-Mins Children’s vitamins, are so popular.

Regenerate joint cartilage and reduce or eliminate arthritis pain

The most common type of arthritis is osteoarthritis.  Osteoarthritis (OA) affects over 21 million Americans and is kneeusually seen in the hips, knees, feet, low-back and hands.

In the early stages OA may start as stiffness or slight limit in range of motion.  As it progresses, pain and swelling set in.

Overuse of the joint is typically what causes osteoarthritis. Repetitive use of the joint contributes to the deterioration of the joint cartilage. As the cartilage dwindles, the ends of the joint bones thicken and move closer together. Bone spurs (called osteophytes) and nodes often form as the condition worsens further reducing mobility and increasing pain and stiffness.

Retaining and regenerating bone cartilage is paramount to addressing osteoarthritis. A published study done in 2007 suggested that use of antioxidants and vitamins that included vitamin C and vitamin E may reduce the risk of bone marrow lesions, benefit cartilage health, and reduce the chances of OA. Additionally, supplementing with omega 3 fish oils, glucosamine, vitamin D3, calcium, magnesium and Pycnogenol® has also been shown to improve or ward-off OA.

Glucosatrin® Bone and Joint Health is a unique glucosamine joint product. It contains glucosamine HCI, vitamin C, vitamin D3, oleanolic acid, Chinese skullcap, plus other synergistic nutrients and herbs. It does not contain chondroitin due to the potential negative side effects that product possesses (which includes hair loss, nausea, diarrhea and heart palpitations). Chondroitin has also been associated with compromised prostate health in men. Glucosatrin® promotes the retention and normal regeneration of bone cartilage with known safe and effective ingredients.

double blind clinical study published in 2007 showed that after two months of use Pycnogenol® improved joint function by 52%, reduce pain by 43% and lessen stiffness by 35%. Isotonix OPC-3®® is the only form of isotonic Pycnogenol® in the world. Drinking this amazing product allows up to 95% of the benefits of Pycnogenol® plus the other ingredients (grape seed, red wine, bilberry and citrus extracts) to be quickly absorbed and put to work in the blood stream. Using Isotonix OPC-3® is an effective way of improving cellular function while reducing inflammation and pain.

Other drinkable Isotonix® products which could help OA are:
Prime™ Joint Support Formula by Isotonix®
Isotonix® Vitamin C
Isotonix® Calcium Plus
Isotonix® Vitamin D with K2

Other capsule products which would be excellent for quelling arthritis difficulties would be:
Curcumin Extreme™
Heart Health Omega III Fish Oil with Vitamin E

Antioxidants Fight Macular Degeneration

Macular degeneration is an eye disease that affects over 10 million Americans.  Age-related Macular DegenerationBlue eye (or AMD) is the most common form found in adults over the age of 55. As the “Baby-Boom” generation continues to age the number of people affected by AMD is anticipated to explode. In 1997, Dr. Carl Kupfer, who was then the Director of the National Eye Institute, publicly stated that macular degeneration will soon take on aspects of an epidemic.

Essentially, macular degeneration is caused when part of the retina deteriorates. The retina is the layer of the eye that transmits light signals to the optic nerve and brain. The macula is the center portion of the retina that renders detailed vision and acuity.

Macular degeneration is considered incurable, however several studies show great promise using oral antioxidants in preventing or impeding this terrible disease.

One such study published March 2009 was conducted by the Friedlander laboratory with mice. The study found that even healthy eyes incur cellular oxidative damage from light. Even small increases in oxidative stress went on to cause cellular retinal damage. Orally-administered antioxidants were remarkably effective at stopping the deterioration.

“People have thought before that antioxidants could have benefits for these conditions, but these data demonstrate clear proof of concept for this treatment approach,” says Dr. Michael Dorrell, a research associate in the Friedlander lab.

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The Power of Isotonic Formulas Compared to Tablets

In 2009 a group of researchers in Italy conducted a study to see if an isotonic formula of a known highly effective Tablets vs liquidsantioxidant behaved differently on the body compared to the same antioxidant in tablet form.

Isotonix OPC-3® is a powdered antioxidant blend that when mixed with the appropriate amount of water becomes “isotonic“.  Isotonic means “same concentration” and is an ideal ratio between solid and liquids that our bodies convert what we ingest into before it can pass into the small intestine.

The four hour test compared Isotonix OPC-3® in a tablet form to Isotonix OPC-3® in its standard isotonic form.  The amount of water that was consumed with the tablet was equal to the amount of water used in the isotonic version.

Results of the test were startling. Levels of free radicals were measured in the blood plasma of test subjects.  The isotonic OPC-3® reduced free radicals six times more in just 10 minutes compared to the tablet version. The tablet form did eventually reduce free radicals substantially as well, but seriously lagged behind the isotonic form thorough out the four hour test .

Researchers concluded that “the findings demonstrate that the flavonoid mixture provided in isotonic OPC-3® is significantly more bio-available in humans, in terms of antioxidant activity than an equivalent mixture in tablet form.”  Overall the isotonic OPC-3® formulation resulted in a stronger antioxidative effect than an equivalent tablet form.

The results of this test highlight the importance of leveraging the advantage of isotonic formulas for established nutritional supplements like: Isotonix® Coenzyme Q10, Isotonix® Resveratrol, ORAC formulas, Isotonix® Vitamin D with K2, Isotonix® Calcium Plus, B Complex, Vitamin C, Acai, Probiotics, Isotonix® OPC-3 Beauty Blend, Multivitamins, Isotonix® Prenatal Multivitamin, Children’s vitamins, Digestive Enzymes, L-Tryptophan, Blood SugarVision formulas, Anti-aging and Joint Health Formulas. Reducing the amount of work the body needs to do in order to receive the nutritional benefits of these products provides significant “bottom line” results.

Absorbing Resveratrol is the Key

Michael J. Fox was recently on Oprah discussing the progress his Parkinson’s research foundation has made lock-and-keyseeking treatments for this degenerative disease. He referenced promising results Dr. Benjamin Wolozin discovered using the grape skin extract known as resveratrol.

In the grant abstract written for Michael J. Fox’s Parkinson’s Research Foundation, Dr. Wolozin discusses synthetic resveratrol formulas which are under production by the biotech-nology company Sirtris and states: “Despite its popular appeal, resveratrol suffers as a pharmacological compound because it is not absorbed by the body well”.

Fortunately another company has already tackled the absorption issues related to natural compounds like resveratrol and pycnogenol. The company is Isotonix® and they have addressed the human digestive process by providing nutrients in patented natural isotonic solutions. If a vitamin or antioxidant is delivered in an isotonic form, the body can receive maximum value in the shortest amount of time. Providing resveratrol, vitamins and other antioxidants by isotonic delivery is ideal for our digestive systems – natural, gentle, potent and effective.

Isotonix® Resveratrol is a combination of three patented ingredients combined in a synergistic formula.  They are Resveravine®, BioVin®, and VitaBlue®. A detailed description of this amazing combination is chronicled in my post “What makes Isotonix® Resveratrol Special“.

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