Studies show natural Resveratrol & Curcumin inhibit Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is a systemic chronic autoimmune disease that usually attacks the joints but can also turn against other systems of the body like the eyes, lungs, heart and nerves. RA is distinguished by developing in a symmetrical pattern (both hands, wrists, hips, etc.). Rheumatoid arthritis affects approximately 1% of the population, is most often seen in women, but tends to be more virulent in men. Juvenile Rheumatoid Arthritis (JRA) affects roughly 50,000 infants, children and teenagers in the US. Rheumatoid arthritis in children is sometimes referred to as Juvenile Idiopathic Arthritis (JIA).

In autoimmune disorders the immune system malfunctions and attacks healthy cells in the body. RA is an autoimmune disease where unique cells called synovial fibroblasts or RASFs develop, invade and destroy tissue.

While antioxidant interventions have been shown to benefit RA in general, newer studies exploring the reduction and/or elimination of synovial fibroblasts in rheumatoid arthritis have yielded interesting outcomes.

The American College of Rheumatoidology published a 2007 study which set out to observe the behavior of natural resveratrol on human synovial fibroblasts. The study observed that natural resveratrol disrupted and triggered cellular death in synovial fibroblasts and concluded that resveratrol may be a “novel therapeutic agent for rheumatoid arthritis”.

Curcumin is another natural compound with potential for helping RA as well. While the anti-inflammatory aspects of curcumin have been well documented and studied in animals, to date only a few human trials have been completed. However, the results of a study of eighteen RA patients using 1200 mg of curcumin daily for two weeks found significantly less morning stiffness, joint swelling and improved walking time compared to another RA group using NSAID therapy (300 mg of phenzlbutazone daily).

A 2009 study focused on using resveratrol and curcumin together and proposed that these two natural substances be used in unison to reduce inflammation in osteoarthritis.

An important aspect of natural resveratrol and curcumin is that these compounds tend to have low bioavailability. Therefore, the quality of a resveratrol or curcumin supplement is paramount if it to be utilized effectively. Absorption is key.

Isotonix® Resveratrol has a synergistic blend of three patented forms of resveratrol (BioVin® Advanced, VitaBlue®, and Resveravine®). Isotonix® Resveratrol is also delivered in a drinkable isotonic form which provides up to 95% absorption into the bloodstream in approximately 5 minutes. Read more on what makes Isotonix® Resveratrol special.

Curcumin Extreme™ contains a patented form of curcumin called BCM-95®. BCM-95® is dramatically more available to the body than standard forms of curcumin. Read more on what makes Curcumin Extreme™ unique.

1 Comment

  1. Engineered for Health » Blog Archive » What is your Gout trying to tell you? said,

    April 16, 2012 at 8:14 pm

    […] by the Intl. Aloe Science Council. Isotonix® Resveratrol – Superior isotonic delivery of the three best patented forms of resveratrol extracts. Curcumin Extreme™ – Contains BCM-95®, which is 6-8 times more bioavailable than […]

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